Formulation And Antibacterial Effectiveness Test Leaf Magrove Ethanol Extract Toothpaste ( Rhizophora Mucronata) Against The Bacteria Streptococcus Mutans

Abstract

Mangrove plants that grow abundantly along the coast are widely known for blocking waves and protecting coastal ecosystems. However, the use of mangrove plants is still limited and tends to focus on the function of physical protection against coastal abrasion so that parts of the mangrove plant such as masi leaves are rarely known about their benefits among the public. This research aims to formulate ethanol extract of mangrove leaves ( Rhizophora mucronata ) into a toothpaste preparation and test its antibacterial activity against the growth of Streptococcus mutans bacteria using the paper disc method. In this research, 4 toothpaste formulations were made with different concentrations, namely F0 (without extract), FI (10%), FII (15%) and FIII (20%). Then a physical stability test was carried out on the toothpaste preparation for 4 weeks including organoleptic tests, homogeneity, pH, spreadability, foam height, viscosity of each of the 4 formulas, showing that the results met the stability requirements of the toothpaste preparation. Furthermore, testing the antibacterial activity of toothpaste preparations with concentrations of 10%, 15%, 20% and K-, K+ showed that the average diameter of the inhibition zone formed was 3mm, 3.38 mm, 5.75 mm and 1.66 mm. , 5.16mm. It can be concluded that the ethanol extract of mangrove leaves ( Rhizophora mucronata ) can be formulated into a toothpaste preparation and can provide maximum antibacterial effect, namely at a concentration of 20% at 5.75 mm.