Formulation Of Combined Antioxidant Serum Preparation Patikala (Etlingera Elatior) Leaves Extract And Black Cumin Seeds Extract (Nigella Sativa) By Dpph Method

Abstract

Patikala leaves (Etlingera elatior) and black cumin seeds (Nigella sativa) are plants that are efficacious as antioxidants, so they can be used in the manufacture of drugs and cosmetics. One preparation that is widely used in beauty products is facial serum. The purpose of this study is to formulate these natural ingredients to determine the most optimum formula and preparation as an antioxidant by making F0 in the form of formulations without extracts, F1 with patikala leaf extracts (Etlingera elatior) and black cumin seeds (Nigella sativa) respectively (15%: 1.5%), F2 (20%: 2%), and F3 (25%: 2.5%). This research is an experimental research. Physical properties test with an average replication in the form of organoleptic test, homogeneity, pH, spreadability, adhesiveness, viscosity, and protective ability test. Serum preparations with both active substances can affect the physical properties of the preparation with results that meet the requirements or not in the preparation of facial serum. The preparation is also not irritating in all formulas, and the most preferred preparation is F0. The IC50 value for the best antioxidant test was found in F2 at 7,125189 µg/mL (very strong).